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Sperm Count Increase in Male Patients With Low Testosterone Levels The presence of any androgenic agents or their derivatives can increase the levels of the male hormone testosterone. This can increase the sperm count in the male testicles and even reduce sperm count in other parts of the body. The incidence of fertility issues such as low fertility, reduced sperm count, and testicular abnormalities have been observed in the presence of androgens and testosterone in human sperm as a side effect. This does not appear to be related to the presence of other androgens (such as estrogen) but these changes are not reversible. If a patient with low testosterone levels does not improve with the use of testosterone patches and may need to return for further testosterone therapy, further testing (e, .
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